JOIN GENTIDE 加入睿联生物科技

Build the future of AI-driven drug discovery 共建 AI 驱动新药发现 的未来

We are assembling a world-class team of scientists, engineers, and drug developers in Shanghai, Singapore, and San Jose. If you want to work at the frontier of AI and structural biology to build therapies that genuinely matter — we want to hear from you. 我们正在上海、新加坡与圣何塞组建世界级科学家、工程师与新药开发者团队。 如果你希望站在 AI 与结构生物学的最前沿,开发真正有意义的创新药物, 我们期待与你相遇。

View Open Roles 查看开放岗位 Send Your CV 发送简历
Why GenTide 为什么选择睿联

A rare kind of company to work at 一家少见的公司

🧬

Real science, real impact 真实科学,真实影响

Every team member works on programs with a direct path to patients. Our pipeline targets metabolic disease, pain, oncology, and aging — four of the largest unmet needs in medicine. 每位团队成员的工作都与直接到达患者的管线相连。我们的研发管线聚焦 代谢疾病、疼痛、肿瘤与衰老——医学中四大最重要的未满足需求。

🤖

AI-Native from day one 从第一天就 AI-Native

You will work with diffusion models, GNNs, and Cryo-EM structural data in a closed-loop system — not as a side project, but as the core engine of everything we do. 你将在一个真实闭环系统中使用扩散模型、GNN 与冷冻电镜结构数据—— 这不是附属项目,而是我们一切工作的核心引擎。

🌐

Global from the start 生来就是全球化

Offices in Shanghai, Singapore, and San Jose. Dual NMPA + FDA IND filing capability. You will work with and for the global market from day one. 上海、新加坡、圣何塞三地办公。NMPA + FDA 中美双报能力。 从第一天起,你就在为全球市场工作。

🚀

Early-stage, high-ownership 早期阶段,高度参与

We are at the founding stage. Every hire shapes what GenTide becomes. You will have real ownership, real decisions, and real accountability. 我们处于创始阶段。每一位招募的人都在塑造睿联的未来。 你将拥有真实的所有权、真实的决策权与真实的责任感。

Open Positions 开放岗位

Now hiring — Phase 1 core team 现招募 —— 阶段一核心团队

All roles are based in Shanghai unless otherwise noted. Relocation support available. 所有岗位均位于上海,特别注明除外。提供搬迁支持。

🤖 AI & Computational Drug Discovery 🤖 AI 计算药物发现
AI Algorithm Engineer — Molecular Generation AI 算法工程师(结构感知分子生成)
Shanghai上海 Full-time全职

Core of the DTBL Design loop. You will develop and deploy generative models for structure-aware 3D molecular design, directly powering all four pipeline programs. DTBL Design 环节核心。你将开发并部署结构感知三维分子生成模型,直接驱动四条管线。

Must have必备
  • Diffusion models / Flow Matching (DiffSBDD / SurfGen / PropMolFlow)扩散模型 / Flow Matching(DiffSBDD / SurfGen / PropMolFlow)
  • SE(3)-equivariant GNN architecturesSE(3) 等变 GNN 架构
  • RDKit + PyTorch GeometricRDKit + PyTorch Geometric
  • REINVENT 4 or multi-property SMILES optimizationREINVENT 4 或多性质 SMILES 优化
Nice to have加分项
  • Publication record in AIDD or structural MLAIDD 或结构 ML 相关发表经历
  • Experience with protein-ligand docking (DiffDock)蛋白-配体对接经验(DiffDock)
AI Algorithm Engineer — Activity & ADMET Prediction AI 算法工程师(活性 / ADMET 预测)
Shanghai上海 Full-time全职

Core of the DTBL Learn loop. You will build and maintain multi-task SAR models and ADMET prediction pipelines that route every generated molecule through a druggability filter before synthesis. DTBL Learn 环节核心。你将构建并维护多任务 SAR 模型与 ADMET 预测管线, 对每个生成分子在合成前完成成药性过滤。

Must have必备
  • Chemprop (message-passing GNN) + ADMET-AI stackChemprop(消息传递 GNN)+ ADMET-AI 技术栈
  • Multi-task SAR modeling多任务 SAR 建模
  • TDC benchmark datasetsTDC 基准数据集使用经验
Nice to have加分项
  • Boltz-2 structure-affinity joint predictionBoltz-2 结构-亲和力联合预测经验
  • Active learning / Bayesian optimization主动学习 / 贝叶斯优化
Scientific Data Engineer 科学数据工程师
Shanghai上海 Full-time全职

The hidden core of the DTBL loop. You will own dry-wet experiment data standardization, feature engineering, and version management — the data quality layer that determines whether our AI models improve or stagnate. Industry data shows 68% of AI projects fail due to poor data quality; this role exists to ensure GenTide is not one of them. DTBL 闭环的隐性核心。你将负责干湿实验数据标准化入库、特征工程与版本管理—— 这一数据质量层决定我们的 AI 模型是持续进步还是停滞不前。 行业数据显示 68% 的 AI 项目因数据质量差而失败;这个岗位就是为确保睿联不是其中之一。

Must have必备
  • Data pipeline engineering (Python, SQL)数据管道工程(Python, SQL)
  • Scientific data familiarity (assay data, SMILES, bioactivity)科学数据理解(活性数据、SMILES、生物活性)
  • Data versioning tools (DVC, MLflow, or equivalent)数据版本管理工具(DVC、MLflow 或同类)
Nice to have加分项
  • Experience in pharma/biotech lab informatics药企 / 生物技术实验室信息化经验
  • Familiarity with ELN or LIMS systemsELN 或 LIMS 系统使用经验
⚗️ Process Chemistry & Analytics ⚗️ 合成工艺与药物分析
Peptide Synthesis Researcher 多肽合成研究员
Shanghai上海 Full-time全职

The wet-lab backbone of the GLP-1 and β2-AR programs. You will translate AI-designed peptide sequences into synthesized, characterized compounds — closing the Design → Test loop and feeding real activity data back into our models. GLP-1 与 β2-AR 管线湿实验的核心支撑。你将把 AI 设计的多肽序列转化为合成、表征完备的化合物,闭合 Design → Test 循环,并将真实活性数据反哺模型迭代。

Must have必备
  • 3+ years of peptide synthesis experience; proficient in Fmoc/t-Boc solid-phase and liquid-phase strategies三年以上多肽合成经验;精通Fmoc/t-Boc固相及液相合成策略
  • Skilled in preparative RP-HPLC, membrane separation, ion-exchange chromatography, MS characterization, and chiral analysis熟练掌握制备HPLC、膜分离、离子交换色谱、质谱表征及手性分析
  • Bachelor's degree or above in Chemistry, Organic Chemistry, or Pharmaceutical Chemistry化学、有机化学、药物化学等相关专业本科及以上学历
Nice to have加分项
  • Experience supporting IND CMC documentation for peptide APIs参与过多肽原料药IND CMC资料撰写
  • Familiarity with peptide impurity profiling (related substances, residual solvents)了解多肽药物杂质研究(有关物质、残留溶剂等)
Peptide Purification Researcher 多肽纯化研究员
Shanghai上海 Full-time全职

Responsible for crude peptide purification, refining, and freeze-drying — providing qualified peptide products for drug discovery and ensuring compliance with domestic and international regulatory standards. 负责多肽药物粗肽的纯化、精制、冻干等工艺,为新药发现提供质量合格的多肽产品,确保产品质量符合国内外法规要求。

Must have必备
  • Bachelor's degree or above in Chemistry, Biochemistry, Analytical Chemistry, Pharmaceutics, or related fields; 3+ years of peptide purification experience化学、生物化学、分析化学、药学等相关专业本科及以上学历;三年以上多肽纯化工作经验
  • Proficient in membrane filtration and chromatographic purification technologies, including affinity/ion-exchange chromatography development and tangential flow filtration (TFF)精通膜过滤和层析纯化方法,包括亲和/离子交换等层析方法开发、切向流过滤(TFF)等纯化工艺
  • Skilled in conventional analytical methods (SDS-PAGE, HPLC, UV280, ELISA, HCP, HCD) and instruments (HPLC, UPLC, LC-MS, GC); proficient in RP, SEC, IEC techniques掌握SDS-PAGE、HPLC、UV280、ELISA、HCP、HCD检测等常规分析方法;熟练操作HPLC、UPLC、LC-MS、GC仪器,精通RP、SEC、IEC等技术
Nice to have加分项
  • Experience in purification scale-up process development and validation; background in technology transfer or industrialization support有纯化放大工艺开发与验证经验;具备技术转移或产业化支持背景
  • Experience supporting IND application dossier compilation for peptide drug substances参与过多肽药物IND申报资料撰写
Organic Synthesis Researcher 有机合成研究员
Shanghai上海 Full-time全职

Critical to the Nav1.8 and TKI programs. You will take AI-proposed small molecule scaffolds from design to synthesized candidate — independently owning route design, multi-step synthesis, and process scale-up through to IND-enabling studies. Nav1.8 与 TKI 管线的关键角色。你将把 AI 提出的小分子骨架从设计推进至合成候选物,独立主导路线设计、多步合成及工艺放大,直至支持IND申报。

Must have必备
  • Solid theoretical foundation in organic chemistry with 3+ years of hands-on multi-step synthetic experience扎实有机化学理论基础,三年以上多步有机合成实操经验
  • Capable of independently designing synthetic routes and troubleshooting complex reactions能独立设计合成路线,有解决复杂反应问题的能力
  • Bachelor's degree or above in Chemistry, Organic Chemistry, or Pharmaceutical Chemistry化学、有机化学、药物化学等相关专业本科及以上学历
Nice to have加分项
  • Experience preparing process technical packages for technology transfer有工艺技术包撰写及技术转移经验
  • Familiarity with kinase inhibitor or ion channel modulator chemistry熟悉激酶抑制剂或离子通道调节剂相关化学背景
Analytical Method Development Researcher 药物分析研究员
Shanghai上海 Full-time全职

The analytical quality layer that keeps the DTBL loop honest. You will build and own the purity, assay, and impurity characterization methods that validate every synthesized compound — the data backbone for both internal decision-making and IND regulatory submissions. 保障 DTBL 闭环数据可信度的分析质量层。你将构建并主导纯度、含量及杂质表征方法,验证每一个合成化合物——为内部决策与IND法规申报提供数据基础。

Must have必备
  • 3+ years of analytical R&D for peptide or small molecule API projects; proficient in HPLC, UPLC, LC-MS, GC三年以上多肽或小分子原料药项目分析经验;熟练操作HPLC、UPLC、LC-MS、GC
  • Experienced in independently leading method development and validation (RP, SEC, IEC); familiar with domestic and international regulatory compliance requirements有独立主导方法开发与验证经历(RP、SEC、IEC);熟悉国内外法规合规要求
  • Bachelor's degree or above in Chemistry, Analytical Chemistry, or Pharmaceutical Analysis化学、分析化学、药物分析等相关专业本科及以上学历
Nice to have加分项
  • Experience supporting IND analytical sections for NMPA or FDA submissions参与过NMPA或FDA IND申报分析部分资料撰写
  • Familiarity with peptide-specific analytical challenges (chiral analysis, aggregation, oxidation)了解多肽特异性分析挑战(手性分析、聚集、氧化等)
Drug Screening Researcher 药物筛选研究员
Shanghai上海 Full-time全职

Responsible for screening drug physiological activity — identifying candidate substances with expected pharmacological activity on specific biological targets through systematic and standardized experimental methods. This role lays the foundation for preclinical and clinical research, reduces R&D risk, and directly feeds activity data back into the DTBL loop. 负责药物生理活性筛选,通过系统化、规范化的实验手段甄别出对特定生物靶点具有预期药理活性的候选物质,为后续临床前与临床研究奠定基础,降低研发风险、提高新药发现效率,并将真实活性数据直接反哺DTBL闭环。

Must have必备
  • Bachelor's degree or above in Pharmaceutical Sciences, Pharmacology, Bioengineering, Cell Biology, Molecular Biology, or related fields; 3+ years of drug screening experience本科及以上学历,药学、药理学、生物工程、细胞生物学、分子生物学等相关专业;三年以上药物筛选相关经验
  • Proficient in high-throughput and in vitro pharmacological screening workflows; candidates with experience in small molecules, peptides, small nucleic acids, or natural product screening are preferred熟悉高通量筛选、体外药理筛选流程;有小分子、多肽、小核酸或天然产物筛选经验者优先
  • Proficiency in cell culture, enzymatic detection, qPCR, Western Blot, and flow cytometry; able to independently design and execute screening experiments including enzyme activity, receptor binding, cell proliferation/apoptosis, and signal pathway assays熟练掌握细胞培养、酶学检测、荧光定量(qPCR)、蛋白印迹(Western Blot)、流式细胞术等实验技术;能独立设计并执行酶活性筛选、受体结合、细胞增殖/凋亡、信号通路检测等实验
Nice to have加分项
  • Familiar with the construction and optimization of drug screening models; experience operating and maintaining HTS instruments (microplate readers, workstations)熟悉药物筛选模型构建与优化;了解高通量筛选仪器(酶标仪、工作站等)操作与维护者优先
  • Good data analysis skills with Excel and GraphPad Prism; familiar with PubMed/CNKI literature retrieval; understanding of GLP norms and new drug R&D regulatory requirements能使用Excel、GraphPad Prism进行数据统计与作图;熟悉PubMed、CNKI等文献检索工具;了解新药研发流程、GLP规范及相关法规
💻 Platform Engineering 💻 平台工程
Software Engineer — Platform & Infrastructure 软件工程师(平台与基础设施)
Shanghai上海 Full-time全职

The DTBL loop runs on software. You will design and build the internal platform that connects AI models, wet-lab workflows, and data pipelines into a single coherent system — making it faster and safer to iterate from molecule design to experimental result. This is a generalist engineering role with high ownership: you will work across backend services, internal tooling, and cloud infrastructure. DTBL 闭环依赖软件运转。你将设计并构建连接 AI 模型、湿实验工作流与数据管线的内部平台—— 让从分子设计到实验结果的每一次迭代更快、更可靠。 这是一个高度自主的全栈工程岗位,涵盖后端服务、内部工具与云基础设施建设。

Must have必备
  • 3+ years of backend or full-stack engineering; strong API design and service architecture skills3 年以上后端或全栈工程经验;具备扎实的 API 设计与服务架构能力
  • Cloud infrastructure experience (AWS / GCP / Alibaba Cloud); comfortable with containerization and CI/CD pipelines云基础设施经验(AWS / GCP / 阿里云);熟悉容器化与 CI/CD 流水线
  • Able to work with data-intensive systems: task queues, job scheduling, async workflows能处理数据密集型系统:任务队列、作业调度、异步工作流
Nice to have加分项
  • Experience building internal tools or platforms in a biotech, lab automation, or research computing environment有生物技术、实验室自动化或科研计算环境中构建内部工具/平台的经验
  • Familiarity with ML model serving (FastAPI, Triton, BentoML) or MLOps tooling了解 ML 模型服务化(FastAPI、Triton、BentoML)或 MLOps 工具链
  • Frontend experience (React / Next.js) for building researcher-facing dashboards具备前端开发能力(React / Next.js),可开发面向科研人员的可视化仪表板
AI Agent Engineer AI 智能体工程师
Shanghai上海 Full-time全职

As an AI Agent Engineer, you will design and implement autonomous agentic workflows that orchestrate our drug discovery models. You will be responsible for creating robust systems where LLMs interact with complex scientific tools, databases, and APIs. 作为 AI 智能体工程师,你将设计和实现自主智能体工作流,以编排我们的药物发现模型。你将负责创建稳健的系统,让大语言模型(LLM)与复杂的科学工具、数据库和 API 进行交互。

Must have必备
  • Hands-on experience in AI Agent development, good understanding of LLM具备 AI Agent 开发方面的实践经验,对 LLM 有深入的了解
  • Demonstrated expertise in prompt engineering, advanced RAG architectures, and complex function calling/tool integration在提示词工程、高级 RAG 架构以及复杂的工具调用(Function Calling)与集成方面具备成熟经验
  • Solid backend software engineering fundamentals and robust API integration skills扎实的后端软件工程基础及强大的 API 集成能力
Nice to have加分项
  • Background in computational biology or cheminformatics具有计算生物学或化学信息学背景
  • Contributions to open-source AI or agent projects曾为开源 AI 或智能体项目做出贡献
  • Experiences in LLM training or fine-tuning有过大语言模型训练或者精调的经验
🛠️ Operations & Administration 🛠️ 运营与行政
Administrative Assistant (HR & IP Affairs) 行政助理(人事与专利事务)
Shanghai上海 Full-time全职

A founding-stage company runs on the people and systems that hold it together. You will be the operational backbone — keeping the team focused on science by owning HR workflows, IP filing coordination, government liaison, and the day-to-day infrastructure that lets researchers do their best work. 创始阶段的公司靠人和系统运转。你将是运营核心——通过主导人事流程、专利申请协调、政府对接与日常基础设施管理,让科学家们专注于研发本身。

Must have必备
  • Bachelor's degree or above; 2+ years in administrative, HR, or operations roles本科及以上学历;2年以上行政、人事或运营相关工作经验
  • Strong English proficiency for cross-border communication; excellent written and documentation skills较好的英语水平,可用于跨国沟通;具备良好的公文写作和文字表达能力
  • Detail-oriented with strong coordination ability across multiple concurrent workstreams细心严谨,能同时协调多条并行事务
Nice to have加分项
  • Experience with patent filing coordination or IP agency liaison in a pharma/biotech context有药企/生技背景的专利申请协调或知识产权代理对接经验
  • Familiarity with Shanghai Zhangjiang R&D grant programs or talent policy applications熟悉上海张江科研经费申请或人才政策申报流程

Ready to apply? 准备好申请了吗?

Send your CV and cover letter with subject format: Position Title – Name – Years of Experience. Please submit in PDF format and indicate your expected salary and availability. Qualified candidates will be contacted within 2 weeks. 请将简历及求职信发送至以下邮箱,邮件主题格式:应聘职位名称 – 姓名 – 工作年限。 简历请使用PDF格式,并注明期望薪资范围及可到岗时间。符合条件的候选人将在2周内收到面试通知。

Send CV to business@gentide.com 发送简历至 business@gentide.com